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Latest Genetics News From News-Medical.Net Total news: 10
Last news: August 31, 2007 03:00:00
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| Mechanism By Which Transcription Factor Controls Gene Expression Demonstrated By Conaway Lab
August 30, 2007 22:00:00The Conaway Lab -- led by Joan Conaway, Ph.D., and Ron Conaway, Ph.D., Investigators -- has published findings that shed light on the role of the much-studied transcription factor YY1 in gene expression. Yong Cai, Ph.D., Research Specialist I, and Jingji Jin, Ph.D., Senior Research Associate, are the papers coequal first authors.The paper, "YY1 Functions with INO80 to Activate Transcription," has been posted to the Web site of Nature Structural & Molecular Biology. 26. [click link for full article] - [Read more] |
| Reprogrammed Embryonic Stem Cells Identified By Appearance Alone
August 30, 2007 17:00:00Some scientific results are hard to spot, especially in genetic research. Often scientists are unable to physically see if the gene they inserted into a cell has produced the desired trait. To overcome this problem researchers use various genetic markers that contain pieces of foreign DNA that cause cells to, for example, glow when exposed to ultraviolet light. [click link for full article] - [Read more] |
| Fingolimod shows promise in 2 lethal leukemias
August 30, 2007 09:29:00A new study suggests that an experimental drug being tested for the treatment of multiple sclerosis and to prevent organ rejection might also help people with certain deadly forms of chronic and acute leukemia. - [Read more] |
| FDA should amend the product information for irinotecan
August 30, 2007 09:29:00Not everyone needs a genetic test before taking the cancer drug irinotecan, and the U.S. Food and Drug Administration should modify its prescription guidelines to say so, according to researchers at the University of North Carolina at Chapel Hill. - [Read more] |
| Genetics of imatinib resistance in acute lymphoblastic leukemia
August 30, 2007 09:10:00In the September 15th issue of Genes & Development, Drs. Richard T. Williams, Willem den Besten, and Charles J. Sherr at Howard Hughes Medical Institute, St. Jude Childrens Research Hospital in Memphis TN, lend new insights into how an aggressive form of acute lymphoblastic leukemia (ALL) develops, and how sensitivity to the targeted chemotherapeutic drug, imatinib, can be diminished through interactions between tumor cells and the host microenvironment. - [Read more] |
| Big leap in genomic screening of blood vessels from patient tissue
August 30, 2007 09:00:00Scientists have developed a new method of capturing a complete genome-wide screening of blood vessel cells in their actual disease state, advancing the potential for genetic research on the tissue responsible for delivering nourishment that can accelerate the growth of both a cancer tumor or wound healing. - [Read more] |
| Mighty mice made mightier
August 30, 2007 09:00:00The Johns Hopkins scientist who first showed that the absence of the protein myostatin leads to oversized muscles in mice and men has now found a second protein, follistatin, whose overproduction in mice lacking myostatin doubles the muscle-building effect. - [Read more] |
| Examining The DNA Of Ancient Bacteria
August 30, 2007 02:00:00A research team has for the first time ever discovered DNA from living bacteria that are more than half a million years old. Never before has traces of still living organisms that old been found. The exceptional discovery can lead to a better understanding of the ageing of cells and might even cast light on the question of life on Mars. The discovery is being published in the current issue of PNAS (Proceedings of The National Academy of Sciences of The United States of America). [click link for full article] - [Read more] |
| "Mighty Mice" Made Mightier
August 30, 2007 00:00:00 The Johns Hopkins scientist who first showed that the absence of the protein myostatin leads to oversized muscles in mice and men has now found a second protein, follistatin, whose overproduction in mice lacking myostatin doubles the muscle-building effect. [click link for full article] - [Read more] |
| Aperts Syndrome Common Even Though Mutation Rate Low
August 29, 2007 23:00:00Aperts syndrome is a condition caused by a mutation that produces fused fingers and toes, and alters cranial development in affected children. It arises spontaneously, but why the mutation that causes this syndrome appears so frequently has been a mystery. In a new study published this week in the open-access journal [click link for full article] - [Read more] |
| San Francisco Chronicle Examines Field Of Direct-To-Consumer Genetic Testing
August 29, 2007 22:00:00The San Francisco Chronicle on Tuesday examined the new field of direct-to-consumer genetic testing, including home-based paternity tests and tests that can determine the gender of a fetus. A paternity test released last week by Sunnyvale, Calif.-based Consumer Genetics can be done without the mans knowledge. [click link for full article] - [Read more] |
| Biomira Initiates Phase 1 Trial Of PX-478 In Patients With Advanced Metastatic Cancers
August 29, 2007 07:00:00Biomira Inc. (Nasdaq: BIOM) (TSX: BRA) announced that the first patient has been enrolled in a Phase 1 clinical trial of PX-478 in patients with advanced metastatic cancer. PX-478 is a novel small molecule compound designed to inhibit the activity of hypoxia inducible factor (HIF)-1 alpha, a transcription factor that controls the expression of a number of genes important for growth and survival of cancer cells. [click link for full article] - [Read more] |
| DNA Test Predicts Harmful Effects Of Cancer Drug
August 29, 2007 07:00:00Not everyone needs a genetic test before taking the cancer drug irinotecan, and the U.S. Food and Drug Administration should modify its prescription guidelines to say so, according to researchers at the University of North Carolina at Chapel Hill. Irinotecan, also known by its brand name Camptosar, is used mainly as a second-line treatment for colorectal cancer, the third most common form of cancer in the United States. [click link for full article] - [Read more] |
| Einstein Researchers Use Novel Approach To Uncover Genetic Components Of Aging
August 29, 2007 03:00:00People who live to 100 or more are known to have just as many-and sometimes even more-harmful gene variants compared with younger people. Now, scientists at the Albert Einstein College of Medicine of Yeshiva University have discovered the secret behind this paradox: favorable "longevity" genes that protect very old people from the bad genes harmful effects. The novel method used by the researchers could lead to new drugs to protect against age-related diseases. [click link for full article] - [Read more] |
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